Clinical trials are designed to assess the efficacy of pharmacologic compounds. These are usually double-blind, placebo- controlled treatment trials, link to terms though more rarely open-labeled studies are performed. Most recently, these trials use an adjunctive medication approach where the study medication is added to the patient’s current pharmacologic regimen.
The research goals involve the investigation of novel treatments for residual positive and negative symptoms and cognitive impairments. In addition, pharmacologic strategies are being evaluated to address health related co-morbidities such as nicotine addiction, metabolic abnormalities and weight gain.